SCHEMBL19942008

SCHEMBL19942008

Cc1ccc2c(c1)NC(O)CO2

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.49
ALDH1A1 P00352 1/20 0.49
GAA P10253 1/20 0.49
MAPT P10636 1/20 0.49
MMP12 P39900 1/20 0.46
BRD4 O60885 1/20 0.39
CREBBP Q92793 1/20 0.39
CYP19A1 P11511 2/20 0.37
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 1/20 0.35
ADRA2A P08913 1/20 0.34
CA2 P00918 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HCRTR2 O43614 1/20 0.33
PTPN7 P35236 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20888295 0.86 CYP19A1 (0.38) HSD17B10ALDH1A1GAAMAPTMMP12
SCHEMBL19423744 0.86 CYP19A1 (0.38) HSD17B10ALDH1A1GAAMAPTMMP12
SCHEMBL3885063 0.81 ALDH1A1 (0.50) HSD17B10ALDH1A1GAAMAPTMMP12
SCHEMBL31451387 0.81 ALDH1A1 (0.50) HSD17B10ALDH1A1GAAMAPTMMP12
SCHEMBL27663070 0.79 GAA (0.45) HSD17B10ALDH1A1GAAMAPTMMP12
SCHEMBL11237252 0.77 GAA (0.46) HSD17B10ALDH1A1GAAMAPTMMP12
SCHEMBL8544441 0.76 GAA (0.43) HSD17B10ALDH1A1GAAMAPTMMP12
SCHEMBL11564816 0.76 GAA (0.45) HSD17B10ALDH1A1GAAMAPTMMP12
SCHEMBL27484641 0.76 MMP12 (0.46) HSD17B10ALDH1A1GAAMAPTMMP12
SCHEMBL11341890 0.74 CYP19A1 (0.49) HSD17B10ALDH1A1GAAMAPTMMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3458452-B1 HETEROCYCLIC COMPOUNDS USEFUL AS ANTI-BACTERIAL AGENTS AND METHOD FOR PRODUCTION BUGWORKS RES INC (US) 2023-08-30 EP disclosed
EP-3757179-A1 INK COMPOSITION FOR INKJET PRINTING, IMAGE FORMING METHOD, AND RECORDED MATERIAL Fujifilm Corporation (JP) 2020-12-30 EP disclosed
WO-2018039972-A1 INHIBITORS OF CELLULAR METABOLIC PROCESSES AGIOS PHARMACEUTICALS, INC. (US) 2018-03-08 WO disclosed