Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27663070 | 0.88 | GAA (0.45) | GAAHSD17B10ALDH1A1MAPTMMP12 | |
| SCHEMBL11237252 | 0.83 | GAA (0.46) | GAAHSD17B10ALDH1A1MAPTMMP12 | |
| SCHEMBL7300283 | 0.82 | CHEK1 (0.38) | GAACYP19A1CA2PNMTNR3C1 | |
| SCHEMBL7297099 | 0.82 | NR3C2 (0.41) | GAACYP19A1CA2PNMTNR3C1 | |
| SCHEMBL11564816 | 0.82 | GAA (0.45) | GAAHSD17B10ALDH1A1MAPTMMP12 | |
| SCHEMBL7297114 | 0.82 | MTNR1A (0.41) | MAPTCYP19A1USP2CYP3A4 | |
| SCHEMBL8546869 | 0.80 | MMP12 (0.42) | GAAHSD17B10ALDH1A1MAPTMMP12 | |
| SCHEMBL7297828 | 0.78 | GAA (0.55) | GAAHSD17B10ALDH1A1MAPTBRD4 | |
| SCHEMBL19942008 | 0.76 | HSD17B10 (0.49) | GAAHSD17B10ALDH1A1MAPTMMP12 | |
| SCHEMBL19751465 | 0.76 | GAA (0.37) | GAAHSD17B10ALDH1A1MAPTMMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614893-B1 | Benzoxazine derivatives, their preparation and their use in therapy | SYNTHELABO (FR) | 1998-05-27 | — | — | EP | disclosed |
| US-5447928-A | Antiischemic agents and nervous system disorders | SYNTHELABO (FR) | 1995-09-05 | — | — | US | disclosed |
| CN-1099032-A | Benzoxazine derivatives, their preparation and their use in medicine | SYNTHELABO (FR) | 1995-02-22 | — | — | CN | disclosed |
| EP-0614893-A1 | Benzoazine derivatives, their preparation and their use in therapy | SYNTHELABO (FR) | 1994-09-14 | — | — | EP | disclosed |