Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SOD1 | P00441 | 1/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14423980 | 0.89 | CYP2C9 (0.72) | CYP2C9TSHRALDH1A1GAAMAPT | |
| SCHEMBL11793369 | 0.84 | ALDH1A1 (0.43) | CYP2C9TSHRALDH1A1GAAMAPT | |
| SCHEMBL14579980 | 0.84 | ALDH1A1 (0.43) | CYP2C9TSHRALDH1A1GAAMAPT | |
| SCHEMBL19944333 | 0.83 | NQO1 (0.61) | CYP2C9TSHRALDH1A1MAPTLMNA | |
| SCHEMBL19944268 | 0.82 | CYP2C9 (0.49) | CYP2C9TSHRALDH1A1GAAMAPT | |
| SCHEMBL19944241 | 0.81 | CYP2C9 (0.78) | CYP2C9TSHRALDH1A1GAAMAPT | |
| SCHEMBL19944440 | 0.79 | ADRB2 (0.56) | CYP2C9TSHRTDP1 | |
| SCHEMBL7477540 | 0.79 | NPC1 (0.54) | CYP2C9TSHRALDH1A1MAPTLMNA | |
| SCHEMBL18417198 | 0.78 | TSHR (0.58) | CYP2C9TSHRALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL19944724 | 0.78 | KDM4E (0.49) | CYP2C9TSHRALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018041132-A1 | MONOMER, POLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF | 广东东阳光药业有限公司 | 2018-03-08 | — | — | WO | disclosed |