Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19944345 | 0.89 | CYP2C9 (0.55) | CYP2C9TSHRALDH1A1GAARXRA | |
| SCHEMBL10807215 | 0.82 | CYP2C9 (0.60) | CYP2C9TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL31538475 | 0.81 | CYP2C9 (0.64) | CYP2C9TSHRLMNAPOLB | |
| SCHEMBL15801032 | 0.80 | TSHR (0.73) | CYP2C9TSHRALDH1A1LMNA | |
| SCHEMBL3081620 | 0.80 | TSHR (0.73) | CYP2C9TSHRALDH1A1LMNA | |
| SCHEMBL9161169 | 0.79 | TSHR (0.66) | CYP2C9TSHRGAANPC1RAB9A | |
| SCHEMBL15677161 | 0.79 | AR (0.54) | TSHRALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL14579980 | 0.78 | ALDH1A1 (0.43) | CYP2C9TSHRALDH1A1GAARXRA | |
| SCHEMBL11793369 | 0.78 | ALDH1A1 (0.43) | CYP2C9TSHRALDH1A1GAARXRA | |
| SCHEMBL2092477 | 0.77 | RXRA (0.52) | ALDH1A1RXRARXRBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1829876-A1 | NITROGENEOUS TRICYCLIC COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2007-09-05 | — | — | EP | disclosed |