Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11957662 | 0.89 | THRB (0.51) | MAPK1LMNAKDM4EALDH1A1TDP1 | |
| SCHEMBL19944373 | 0.86 | HPGD (0.47) | LMNAKDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL19944466 | 0.85 | CYP2C9 (0.53) | MTNR1AMTNR1BTSHRMAPK1KDM4E | |
| SCHEMBL14546502 | 0.84 | HTR1D (0.48) | MAPK1LMNAKDM4EALDH1A1TDP1 | |
| SCHEMBL4198439 | 0.84 | RXRA (0.46) | MRGPRX4 | |
| SCHEMBL19944469 | 0.84 | MAPK1 (0.48) | TSHRMAPK1KDM4EPOLBALDH1A1 | |
| SCHEMBL4186174 | 0.84 | PTPN7 (0.46) | MAPK1KDM4EALDH1A1TDP1MRGPRX4 | |
| SCHEMBL5085759 | 0.83 | ALDH1A1 (0.45) | LMNAKDM4EPOLBALDH1A1MRGPRX4 | |
| SCHEMBL4194694 | 0.83 | THRB (0.46) | MAPK1LMNAPOLBL3MBTL1GAA | |
| SCHEMBL5088322 | 0.82 | THRB (0.57) | MTNR1AMTNR1BLMNAKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018041132-A1 | MONOMER, POLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF | 广东东阳光药业有限公司 | 2018-03-08 | — | — | WO | disclosed |