Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19944362 | 0.82 | ACACB (0.46) | ALDH1A1THRBKMT2ACYP1A2ACACB | |
| SCHEMBL12607101 | 0.82 | THRB (0.41) | MAOBTHRBCYP1A2CYP2C19AR | |
| SCHEMBL19944346 | 0.81 | THRB (0.48) | MAOBALDH1A1THRBKMT2AGAA | |
| SCHEMBL19944466 | 0.81 | CYP2C9 (0.53) | MAOBALDH1A1L3MBTL1THRBKMT2A | |
| SCHEMBL4759200 | 0.81 | KDM4E (0.40) | MAOBALDH1A1THRBKMT2ACYP2C19 | |
| SCHEMBL13865561 | 0.81 | HRH2 (0.41) | TEAD1TEKTHRBMMP1MMP2 | |
| SCHEMBL5088322 | 0.80 | THRB (0.57) | ALDH1A1TEAD1THRBKMT2AGAA | |
| SCHEMBL19944449 | 0.79 | AR (0.43) | ALDH1A1EPHX2MRGPRX4L3MBTL1HRH3 | |
| SCHEMBL14173315 | 0.78 | THRB (0.44) | ALDH1A1THRBGAACYP1A2ACACB | |
| SCHEMBL19944468 | 0.78 | THRB (0.51) | THRBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018041132-A1 | MONOMER, POLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF | 广东东阳光药业有限公司 | 2018-03-08 | — | — | WO | disclosed |