Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.47 |
| ▸ | PLAU | P00749 | 4/20 | 0.42 |
| ▸ | HPN | P05981 | 4/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.38 |
| ▸ | BMP1 | P13497 | 5/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19944859 | 0.88 | ITGB3 (0.49) | ITGB3ITGA2BPLAUHPNPSMB8 | |
| SCHEMBL15462679 | 0.88 | ITGB3 (0.43) | ITGB3ITGA2BPLAUHPNKDM4E | |
| SCHEMBL20052367 | 0.88 | ITGB3 (0.43) | ITGB3ITGA2BPLAUHPNKDM4E | |
| SCHEMBL20356157 | 0.88 | ITGB3 (0.43) | ITGB3ITGA2BPLAUHPNKDM4E | |
| SCHEMBL20356156 | 0.81 | ITGB3 (0.43) | ITGB3ITGA2BPLAUHPNKDM4E | |
| SCHEMBL1839480 | 0.77 | ITGB3 (0.56) | ITGB3ITGA2BPLAUHPNKDM4E | |
| SCHEMBL1839478 | 0.77 | ITGB3 (0.56) | ITGB3ITGA2BPLAUHPNKDM4E | |
| SCHEMBL20052405 | 0.76 | CASP3 (0.50) | ITGB3ITGA2BPLAUHPNPSMB5 | |
| SCHEMBL20356013 | 0.76 | CASP3 (0.50) | ITGB3ITGA2BPLAUHPNPSMB5 | |
| SCHEMBL15462701 | 0.76 | CASP3 (0.50) | ITGB3ITGA2BPLAUHPNPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697246-B1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | GENESIS TECH LIMITED (BB) | 2018-03-07 | — | — | EP | disclosed |