Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.56 |
| ▸ | PLAU | P00749 | 7/20 | 0.53 |
| ▸ | HPN | P05981 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | MMP9 | P14780 | 3/20 | 0.42 |
| ▸ | MMP12 | P39900 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1839478 | 1.00 | ITGB3 (0.56) | ITGB3ITGA2BPLAUHPNALDH1A1 | |
| Methyl P-Toluenesulfonyl-L-Argininate SCHEMBL2853451 | 0.92 | ITGB3 (0.57) | ITGB3ITGA2BPLAUHPNALDH1A1 | |
| Methyl P-Toluenesulfonyl-L-Argininate SCHEMBL324561 | 0.92 | ITGB3 (0.57) | ITGB3ITGA2BPLAUHPNALDH1A1 | |
| Methyl P-Toluenesulfonyl-L-Argininate SCHEMBL11880215 | 0.91 | ITGB3 (0.56) | ITGB3ITGA2BPLAUHPNALDH1A1 | |
| Methyl P-Toluenesulfonyl-L-Argininate SCHEMBL1034821 | 0.91 | ITGB3 (0.56) | ITGB3ITGA2BPLAUHPNALDH1A1 | |
| SCHEMBL1244355 | 0.89 | ITGB3 (0.60) | ITGB3ITGA2BPLAUHPNALDH1A1 | |
| SCHEMBL17318886 | 0.88 | ITGB3 (0.54) | ITGB3ITGA2BPLAUHPNALDH1A1 | |
| SCHEMBL1509766 | 0.87 | ITGB3 (0.71) | ITGB3ITGA2BPLAUHPNTDP1 | |
| Hydrochloric Acid SCHEMBL7319933 | 0.87 | ITGB3 (0.59) | ITGB3ITGA2BPLAUHPNALDH1A1 | |
| SCHEMBL1509767 | 0.87 | ITGB3 (0.71) | ITGB3ITGA2BPLAUHPNTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8957205-B2 | Cycloalkane carboxamide derivatives and production process of same | SEIKAGAKU CORPORATION (JP) | 2015-02-17 | — | — | US | disclosed |
| US-8829209-B2 | Cycloalkylcarbonylamino acid ester derivative and process for producing the same | SEIKAGAKU CORPORATION (JP) | 2014-09-09 | — | — | US | disclosed |
| WO-2013087785-A2 | BOWMAN-BIRK PROTEASE INHIBITOR (BBI) BINDING PEPTIDES, AND USES THEREOF IN THE SEPARATION, DETECTION OR PURIFICATION OF BBI | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2013-06-20 | — | — | WO | disclosed |
| EP-2604624-A1 | Bowman-Birk protease Inhibitor (BBI) binding peptides, and uses thereof in the separation, detection or purification of BBI. | University College Dublin National University Of Ireland, Dublin (IE) | 2013-06-19 | — | — | EP | disclosed |
| EP-2036920-B1 | CYCLOALKYLCARBONYLAMINO ACID ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | SEIKAGAKU KOGYO CO LTD (JP) | 2011-05-18 | — | — | EP | disclosed |
| US-20090156805-A1 | Cycloalkane Carboxamide Derivatives and Production Process of Same | SEIKAGAKU CORPORATION (JP) | 2009-06-18 | — | — | US | disclosed |
| US-20090137799-A1 | Cycloalkylcarbonylamino Acid Ester Derivative and Process for Producing The Same | SEIKAGAKU CORPORATION (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-2036920-A1 | CYCLOALKYLCARBONYLAMINO ACID ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | SEIKAGAKU CORPORATION (JP) | 2009-03-18 | — | — | EP | disclosed |
| EP-1972615-A1 | CYCLOALKANECARBOXAMIDE DERIVATIVE AND METHOD FOR PRODUCING SAME | SEIKAGAKU CORPORATION (JP) | 2008-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156805-A1 | Cycloalkane Carboxamide Derivatives and Production Process of Same | CTSK, CTSS, CTSB | ITGB3 3742/4885ITGA2B 3231/4885PLAU 527/4885 |
| US-20090137799-A1 | Cycloalkylcarbonylamino Acid Ester Derivative and Process for Producing The Same | CTSK, CTSS, CTSE | ITGB3 3142/4885ITGA2B 3161/4885PLAU 469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.