Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 13/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.47 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.47 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2723774 | 0.91 | FAAH (0.55) | TRPV1FAAHPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL2723735 | 0.86 | TRPV1 (0.73) | TRPV1EPHX2TRPM8NAMPT | |
| SCHEMBL19946410 | 0.83 | TRPV1 (0.47) | TRPV1 | |
| SCHEMBL31679068 | 0.77 | TRPV1 (0.69) | TRPV1EPHX2TRPM8NAMPT | |
| SCHEMBL2723508 | 0.77 | TRPV1 (0.69) | TRPV1EPHX2TRPM8NAMPT | |
| SCHEMBL2724878 | 0.75 | TRPV1 (0.63) | TRPV1FAAHPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL27645808 | 0.74 | NPC1 (0.43) | FAAHEPHX2NAMPT | |
| SCHEMBL2731876 | 0.74 | TRPV1 (0.59) | TRPV1FAAHPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL2727164 | 0.73 | TRPV1 (0.79) | TRPV1EPHX2TRPM8 | |
| SCHEMBL2723660 | 0.73 | TRPV1 (0.79) | TRPV1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635281-B1 | METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF CARDIAC HYPERTROPHY | UNIV HAWAII (US) | 2018-03-14 | — | — | EP | disclosed |