Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 13/20 | 0.51 |
| ▸ | CCNH | P51946 | 12/20 | 0.51 |
| ▸ | MNAT1 | P51948 | 12/20 | 0.51 |
| ▸ | PRKCB | P05771 | 7/20 | 0.48 |
| ▸ | PRKCA | P17252 | 6/20 | 0.48 |
| ▸ | PRKCH | P24723 | 6/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 6/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 6/20 | 0.48 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.48 |
| ▸ | PIM1 | P11309 | 2/20 | 0.48 |
| ▸ | MARK3 | P27448 | 2/20 | 0.48 |
| ▸ | LTK | P29376 | 2/20 | 0.48 |
| ▸ | GRK5 | P34947 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | GSK3A | P49840 | 2/20 | 0.48 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.48 |
| ▸ | JAK3 | P52333 | 2/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2000189 | 0.88 | JAK3 (0.45) | CDK7CCNHMNAT1PRKCBPRKCA | |
| SCHEMBL1994928 | 0.80 | PRKCB (0.44) | CDK7CCNHMNAT1PRKCBPRKCA | |
| SCHEMBL2000755 | 0.80 | PRKCH (0.47) | CDK7CCNHMNAT1PRKCBPRKCA | |
| SCHEMBL1992057 | 0.79 | PRKCH (0.76) | CDK7PRKCBPRKCAPRKCHPRKCQ | |
| SCHEMBL1991636 | 0.78 | PRKCH (0.48) | CDK7PRKCBPRKCAPRKCHPRKCQ | |
| SCHEMBL1991241 | 0.76 | PRKCB (0.41) | CDK7CCNHMNAT1PRKCBPRKCA | |
| SCHEMBL1992070 | 0.75 | PRKCH (0.57) | CDK7PRKCBPRKCAPRKCHPRKCQ | |
| SCHEMBL1998477 | 0.75 | PRKCH (0.56) | CDK7PRKCBPRKCAPRKCHPRKCQ | |
| SCHEMBL2000158 | 0.75 | PRKCH (0.46) | CDK7CCNHMNAT1PRKCBPRKCA | |
| SCHEMBL1991277 | 0.75 | PRKCH (0.54) | CDK7PRKCBPRKCAPRKCHPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079105-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-30 | — | — | WO | disclosed |
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | CDK7 946/4885CCNH 2872/4885MNAT1 2299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.