SCHEMBL2000189

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1994647	0.88	CDK7 (0.51)	JAK3CDK7CCNHMNAT1CDK2
	SCHEMBL1991241	0.80	PRKCB (0.41)	JAK3CDK7CCNHMNAT1CDK2
	SCHEMBL1999111	0.79	PRKCH (0.54)	JAK3CDK7CDK2PRKCBPRKCA
	SCHEMBL1994905	0.76	PRKCH (0.56)	JAK3CDK7CDK2PRKCBPRKCA
	SCHEMBL1994928	0.75	PRKCB (0.44)	JAK3CDK7CCNHMNAT1CDK2
	SCHEMBL1991636	0.75	PRKCH (0.48)	JAK3CDK7CDK2PRKCBPRKCA
	SCHEMBL1992096	0.74	PRKCH (0.53)	JAK3CDK7CDK2PRKCBPRKCA
	SCHEMBL1995687	0.74	PRKCH (0.51)	JAK3CDK7CDK2PRKCBPRKCA
	SCHEMBL1994377	0.74	PRKCH (0.59)	JAK3CDK7CDK2PRKCBPRKCA
	SCHEMBL1992528	0.74	PRKCH (0.59)	JAK3CDK7CDK2PRKCBPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.