Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL200957 | 1.00 | HSD11B1 (0.47) | HSD11B1ALDH1A1HSD11B2EPAS1 | |
| SCHEMBL200160 | 0.97 | HSD11B1 (0.43) | HSD11B1ALDH1A1HSD11B2EPAS1 | |
| SCHEMBL3986309 | 0.90 | ALDH1A1 (0.42) | HSD11B1ALDH1A1 | |
| SCHEMBL199996 | 0.90 | ALDH1A1 (0.42) | HSD11B1ALDH1A1 | |
| Ethylene SCHEMBL774849 | 0.85 | ALDH1A1 (0.39) | HSD11B1ALDH1A1 | |
| SCHEMBL19689443 | 0.83 | ALDH1A1 (0.46) | HSD11B1ALDH1A1 | |
| SCHEMBL5491384 | 0.83 | — | — | |
| SCHEMBL6724992 | 0.83 | ALDH1A1 (0.46) | HSD11B1ALDH1A1 | |
| Methyl Alcohol SCHEMBL4202813 | 0.82 | HSD11B1 (0.39) | HSD11B1ALDH1A1 | |
| SCHEMBL23817028 | 0.82 | HSD11B1 (0.36) | HSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10155777-B2 | Trans-cycloheptenes and hetero-trans-cycloheptenes for bioorthogonal coupling | UNIVERSITY OF DELAWARE (US) | 2018-12-18 | — | — | US | disclosed |
| US-20180072761-A1 | TRANS-CYCLOHEPTENES AND HETERO-TRANS-CYCLOHEPTENES FOR BIOORTHOGONAL COUPLING | UNIVERSITY OF DELAWARE (US) | 2018-03-15 | — | — | US | disclosed |
| US-20180072761-A1 | TRANS-CYCLOHEPTENES AND HETERO-TRANS-CYCLOHEPTENES FOR BIOORTHOGONAL COUPLING | UNIVERSITY OF DELAWARE (US) | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10155777-B2 | Trans-cycloheptenes and hetero-trans-cycloheptenes for bioorthogonal coupling | HCRTR2, HCRTR1, CRHR2 | HSD11B1 1743/4885ALDH1A1 2900/4885HSD11B2 1588/4885 |
| US-20180072761-A1 | TRANS-CYCLOHEPTENES AND HETERO-TRANS-CYCLOHEPTENES FOR BIOORTHOGONAL COUPLING | HCRTR2, HCRTR1, CRHR2 | HSD11B1 1743/4885ALDH1A1 2900/4885HSD11B2 1588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.