Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1991621 | 0.81 | TSHR (0.31) | TSHR | |
| Fluoride Ion SCHEMBL5411127 | 0.78 | ALDH1A1 (0.40) | TSHRLMNATDP1 | |
| SCHEMBL27285776 | 0.76 | TSHR (0.36) | TSHRLMNA | |
| Hydrochloric Acid SCHEMBL5849103 | 0.71 | TSHR (0.33) | TSHR | |
| Water SCHEMBL7549052 | 0.71 | TSHR (0.33) | TSHR | |
| Hydrochloric Acid SCHEMBL28346423 | 0.69 | SLC22A1 (0.40) | TSHR | |
| Water SCHEMBL7941486 | 0.69 | SLC22A1 (0.33) | TSHR | |
| Hydrochloric Acid SCHEMBL1914719 | 0.69 | TSHR (0.38) | TSHRLMNACHRM1AKR1A1CHRM3 | |
| SCHEMBL18721269 | 0.64 | — | — | |
| SCHEMBL1995636 | 0.64 | TSHR (0.45) | TSHRCHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110151355-A1 | POLYMER, POLYMER ELECTROLYTE AND USE OF SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-23 | — | — | US | disclosed |