Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9719666 | 0.84 | PSMD14 (0.42) | LMNA | |
| Hydrochloric Acid SCHEMBL4889265 | 0.84 | PSMD14 (0.42) | LMNA | |
| Hydrochloric Acid SCHEMBL4895294 | 0.84 | PSMD14 (0.42) | LMNA | |
| Hydrochloric Acid SCHEMBL4894359 | 0.84 | PSMD14 (0.42) | LMNA | |
| Hydrochloric Acid SCHEMBL4891156 | 0.84 | PSMD14 (0.42) | LMNA | |
| SCHEMBL8139870 | 0.80 | LMNA (0.43) | LMNA | |
| SCHEMBL8152563 | 0.80 | LMNA (0.43) | LMNA | |
| Hydrochloric Acid SCHEMBL19436589 | 0.79 | PSMD14 (0.42) | LMNA | |
| SCHEMBL27285776 | 0.73 | TSHR (0.36) | TSHRLMNA | |
| Hydrochloric Acid SCHEMBL28346423 | 0.72 | SLC22A1 (0.40) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368592-B1 | COSMETIC COMPOSITION, COSMETIC, AND EXTERNAL PREPARATION FOR SKIN | DOW TORAY CO LTD (JP) | 2025-12-03 | — | — | EP | disclosed |
| US-11820846-B2 | Composition, method of preparing copolymer, and methods and end uses thereof | DOW SILICONES CORPORATION (US) | 2023-11-21 | — | — | US | disclosed |
| EP-2492301-B1 | NOVEL CO-MODIFIED ORGANOPOLYSILOXANE | DOW TORAY CO LTD (JP) | 2023-03-29 | — | — | EP | disclosed |
| US-20220112322-A1 | COMPOSITION, METHOD OF PREPARING COPOLYMER, AND METHODS AND END USES THEREOF | DOW TORAY CO., LTD. (JP) | 2022-04-14 | — | — | US | disclosed |
| EP-2658899-A1 | COSMETIC CONTAINING LIQUID ORGANOPOLYSILOXANE | Dow Corning Toray Co., Ltd. (JP) | 2013-11-06 | — | — | EP | disclosed |
| EP-2515841-A1 | COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION AND COSMETIC CONTAINING THE SAME | Dow Corning Toray Co., Ltd. (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2012091155-A1 | COSMETIC CONTAINING LIQUID ORGANOPOLYSILOXANE | DOW CORNING TORAY CO., LTD. (JP) | 2012-07-05 | — | — | WO | disclosed |
| WO-2011078407-A1 | COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION AND COSMETIC CONTAINING THE SAME | DOW CORNING TORAY CO., LTD. (JP) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11820846-B2 | Composition, method of preparing copolymer, and methods and end uses thereof | BRS3, OXSR1, OXER1 | CHRM1 79/4885CHRM3 32/4885SLC6A3 3587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.