Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5849103 | 0.94 | TSHR (0.33) | TSHR | |
| SCHEMBL28348241 | 0.87 | — | — | |
| Sulfuric Acid SCHEMBL4752456 | 0.83 | CYP3A4 (0.30) | TSHR | |
| SCHEMBL15969554 | 0.81 | TSHR (0.31) | TSHR | |
| Water SCHEMBL7941486 | 0.80 | SLC22A1 (0.33) | TSHR | |
| Iodide SCHEMBL11050168 | 0.79 | OPRM1 (0.37) | TSHR | |
| Hydrochloric Acid SCHEMBL11190139 | 0.72 | LMNA (0.38) | TSHR | |
| SCHEMBL1994789 | 0.71 | TSHR (0.38) | TSHR | |
| SCHEMBL31374472 | 0.71 | DNM1 (0.39) | TSHR | |
| Bromide SCHEMBL29773378 | 0.70 | SLC22A1 (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020146650-A1 | Photographic processing element and image forming method by the use thereof | KONICA CORPORATION (JP) | 2002-10-10 | — | — | US | disclosed |
| US-6455235-B1 | PHOTOGRAPHIC PROCESSING ELEMENT COMPRISING PRECURSOR OF COLOR DEVELOPING AGENT | KONICA CORPORATION (JP) | 2002-09-24 | — | — | US | disclosed |
| EP-1109064-A1 | Photographic processing element and image forming method by the use thereof | KONICA CORPORATION (JP) | 2001-06-20 | — | — | EP | disclosed |