SCHEMBL19949221

SCHEMBL19949221

CCCCCC/C=C\CC(CCO)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.38
ALDH1A1 P00352 2/20 0.38
CNR1 P21554 2/20 0.38
FFAR1 O14842 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38
PRKCE Q02156 1/20 0.36
PRKCQ Q04759 1/20 0.36
PRKCD Q05655 1/20 0.36
PRKCA P17252 1/20 0.36
FAAH O00519 2/20 0.35
TRPV1 Q8NER1 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29706817 1.00 CNR2 (0.38) CNR2ALDH1A1CNR1FFAR1FFAR4
SCHEMBL19949220 1.00 CNR2 (0.38) CNR2ALDH1A1CNR1FFAR1FFAR4
SCHEMBL25424559 0.93 FFAR1 (0.39) CNR2ALDH1A1CNR1FFAR1FFAR4
SCHEMBL17744083 0.88 FFAR1 (0.47) ALDH1A1FFAR1FFAR4FAAHTRPV1
SCHEMBL17743885 0.88 FFAR1 (0.47) ALDH1A1FFAR1FFAR4FAAHTRPV1
SCHEMBL17743888 0.88 FFAR1 (0.47) ALDH1A1FFAR1FFAR4FAAHTRPV1
SCHEMBL17744087 0.88 FFAR1 (0.47) ALDH1A1FFAR1FFAR4FAAHTRPV1
SCHEMBL19949251 0.85 CNR2 (0.42) CNR2ALDH1A1CNR1FFAR1FFAR4
SCHEMBL17743865 0.85 FFAR1 (0.47) FFAR1FFAR4FAAHMAPT
SCHEMBL17743931 0.85 FFAR1 (0.47) FFAR1FFAR4FAAHMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243143-A1 1,3-Fatty Diol Compounds And Derivatives Thereof AGAIN BIO APS (DK) 2025-07-31 US disclosed
US-12304883-B2 1,3-fatty diol compounds and derivatives thereof GENOMATICA, INC. (US) 2025-05-20 US disclosed
EP-4223765-A1 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF Genomatica, Inc. (US) 2023-08-09 EP disclosed
EP-3795576-B1 1,3-FATTY DIOL COMPOUNDS AND GLYCOSYLATED DERIVATIVES THEREOF GENOMATICA INC (US) 2023-06-07 EP disclosed
US-20220098133-A1 1,3-Fatty Diol Compounds And Derivatives Thereof AGAIN BIO APS (DK) 2022-03-31 US disclosed
US-11168046-B2 1,3-fatty diol compounds and derivatives thereof GENOMATICA, INC. (US) 2021-11-09 US disclosed
EP-3795576-A1 1,3-FATTY DIOL COMPOUNDS AND GLYCOSYLATED DERIVATIVES THEREOF Genomatica, Inc. (US) 2021-03-24 EP disclosed
US-20200385325-A1 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF GENOMATICA, INC. (US) 2020-12-10 US disclosed
EP-3512825-B1 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF GENOMATICA INC (US) 2020-10-21 EP disclosed
US-10570074-B2 1,3-fatty diol compounds and derivatives thereof GENOMATICA, INC. (US) 2020-02-25 US disclosed
US-20180072645-A1 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF REG LIFE SCIENCES LLC (US) 2018-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10570074-B2 1,3-fatty diol compounds and derivatives thereof DGAT1, DGAT2, DSG1 CNR2 1978/4885ALDH1A1 215/4885CNR1 2104/4885
US-20250243143-A1 1,3-Fatty Diol Compounds And Derivatives Thereof DGAT1, DGAT2, DSG1 CNR2 1978/4885ALDH1A1 215/4885CNR1 2104/4885
US-20180072645-A1 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF DGAT1, DGAT2, DSG1 CNR2 1978/4885ALDH1A1 215/4885CNR1 2104/4885
US-12304883-B2 1,3-fatty diol compounds and derivatives thereof DGAT1, DGAT2, DSG1 CNR2 1978/4885ALDH1A1 215/4885CNR1 2104/4885
US-11168046-B2 1,3-fatty diol compounds and derivatives thereof DGAT1, DGAT2, DSG1 CNR2 1978/4885ALDH1A1 215/4885CNR1 2104/4885
US-20200385325-A1 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF DGAT1, DGAT2, DSG1 CNR2 1978/4885ALDH1A1 215/4885CNR1 2104/4885
US-20220098133-A1 1,3-Fatty Diol Compounds And Derivatives Thereof DGAT1, DGAT2, DSG1 CNR2 1978/4885ALDH1A1 215/4885CNR1 2104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.