SCHEMBL1994979

SCHEMBL1994979

Cc1ccc2nc3c4ccccc4c4ccccc4c3nc2c1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.50
KDM4E B2RXH2 1/20 0.50
MAPK1 P28482 1/20 0.50
CYP1A2 P05177 3/20 0.45
CYP2A6 P11509 2/20 0.45
TSHR P16473 1/20 0.45
KDM1A O60341 2/20 0.40
GPR3 P46089 1/20 0.39
MAOA P21397 1/20 0.39
ALDH1A1 P00352 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CTSD P07339 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
NPC1 O15118 1/20 0.37
HCRTR1 O43613 1/20 0.37
RAB9A P51151 1/20 0.37
BACE1 P56817 1/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17598973 0.86 L3MBTL1 (0.53) MAPTKDM4EMAPK1CYP1A2CYP2A6
SCHEMBL1010318 0.82 MAPT (0.55) MAPTKDM4EMAPK1CYP1A2CYP2A6
SCHEMBL29645243 0.82 MAPT (0.55) MAPTKDM4EMAPK1CYP1A2CYP2A6
Phenazine SCHEMBL29098643 0.82 MAPT (0.55) MAPTKDM4EMAPK1CYP1A2CYP2A6
SCHEMBL14015461 0.79 CYP1A2 (0.50) MAPTCYP1A2CYP2A6TSHRGPR3
SCHEMBL12578240 0.78 RAB9A (0.49) MAPTMAPK1CYP1A2CYP2A6KDM1A
SCHEMBL29206061 0.77 NQO2 (0.57) MAPTKDM4EMAPK1CYP1A2ALDH1A1
SCHEMBL1998103 0.75 NQO2 (0.60) MAPTKDM4ECYP1A2GPR3ALDH1A1
SCHEMBL11694058 0.74 PRMT5 (0.54) MAPTKDM4EMAPK1CYP1A2CYP2A6
SCHEMBL668870 0.73 ALDH1A1 (0.50) MAPTKDM4ECYP1A2CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090274966-A1 PHENAZINE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-11-05 US claimed
US-7960079-B2 Phenazine containing photoconductors XEROX CORPORATION (US) 2011-06-14 US disclosed
US-7960079-B2 Phenazine containing photoconductors XEROX CORPORATION (US) 2011-06-14 US disclosed
US-7960079-B2 Phenazine containing photoconductors XEROX CORPORATION (US) 2011-06-14 US disclosed
US-20090274966-A1 PHENAZINE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-11-05 US disclosed
US-20090274966-A1 PHENAZINE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-11-05 US disclosed
US-20090274966-A1 PHENAZINE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-11-05 US disclosed