Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 12/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.35 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1989949 | 0.85 | PTGDR2 (0.57) | PTGDR2PPARAPPARGRORCMEN1 | |
| SCHEMBL1995018 | 0.82 | PTGDR2 (0.48) | PTGDR2RORCMEN1KMT2AABCC9 | |
| SCHEMBL1988977 | 0.80 | PTGDR2 (0.45) | PTGDR2PPARAPPARG | |
| SCHEMBL1995021 | 0.79 | PTGDR2 (0.41) | PTGDR2RORCMEN1KMT2AABCC9 | |
| SCHEMBL1989639 | 0.79 | MEN1 (0.46) | PTGDR2MEN1KMT2A | |
| SCHEMBL1989828 | 0.75 | PTGDR2 (0.40) | PTGDR2PPARAPPARGABCC9ABCC8 | |
| SCHEMBL2356020 | 0.74 | MMP2 (0.40) | PTGDR2 | |
| SCHEMBL1690289 | 0.73 | PTGDR2 (0.60) | PTGDR2 | |
| SCHEMBL1995373 | 0.73 | HTR2A (0.45) | PTGDR2MEN1KMT2A | |
| SCHEMBL2351215 | 0.72 | PTGDR2 (0.43) | PTGDR2PPARAPPARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008350-B2 | Biphenyloxyacetic acid derivatives for the treatment of respiratory disease | ASTRAZENECA AB (SE) | 2011-08-30 | — | — | US | disclosed |
| US-20110152374-A1 | Biphenyloxyacetic Acid Derivatives for the Treatment of Respiratory Disease | ASTRAZENECA AB (SE) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152374-A1 | Biphenyloxyacetic Acid Derivatives for the Treatment of Respiratory Disease | BPGM, PPARA, HPD | PTGDR2 568/4885PPARA 2/4885PPARG 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.