Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.53 |
| ▸ | BRD4 | O60885 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19951277 | 0.81 | ALDH1A1 (0.48) | BRD4GAAKMT2ANPC1POLB | |
| SCHEMBL19951196 | 0.76 | LMNA (0.59) | BRD4GAAKDM4EMEN1KMT2A | |
| SCHEMBL19951210 | 0.75 | KDM4E (0.49) | BRD4GAAKDM4EMEN1KMT2A | |
| SCHEMBL19951220 | 0.75 | KLKB1 (0.44) | MBOAT4GAAKDM4EMEN1KMT2A | |
| SCHEMBL17515050 | 0.71 | BRD4 (0.69) | MBOAT4BRD4P2RX7PARP1POLB | |
| SCHEMBL16832224 | 0.69 | MAPT (0.49) | GAAKDM4EMEN1KMT2AGFER | |
| SCHEMBL19837407 | 0.69 | MBOAT4 (1.00) | MBOAT4 | |
| SCHEMBL16832680 | 0.69 | KDM4E (0.62) | MBOAT4GAAKDM4EMEN1KMT2A | |
| SCHEMBL19951266 | 0.68 | KDM4E (0.47) | GAAKDM4EMEN1KMT2AGFER | |
| SCHEMBL8403540 | 0.68 | BRD4 (0.62) | BRD4GAAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10357477-B2 | Anticancer compounds | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2019-07-23 | — | — | US | disclosed |
| US-20180071258-A1 | ANTICANCER COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180071258-A1 | ANTICANCER COMPOUNDS | RB1, MCL1, TP53 | MBOAT4 4154/4885BRD4 642/4885GAA 1917/4885 |
| US-10357477-B2 | Anticancer compounds | RB1, MCL1, TP53 | MBOAT4 4154/4885BRD4 642/4885GAA 1917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.