Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 3/20 | 0.44 |
| ▸ | PRKACG | P22612 | 3/20 | 0.44 |
| ▸ | PRKACB | P22694 | 3/20 | 0.44 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 10/20 | 0.39 |
| ▸ | PRKCG | P05129 | 6/20 | 0.39 |
| ▸ | PRKCB | P05771 | 6/20 | 0.39 |
| ▸ | PRKCA | P17252 | 6/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.38 |
| ▸ | GHSR | Q92847 | 3/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.36 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1992095 | 0.96 | CAMK2D (0.43) | PRKACAPRKACGPRKACBCAMK2DSIRT2 | |
| SCHEMBL1990609 | 0.91 | CAMK2D (0.44) | PRKACAPRKACGPRKACBCAMK2DSIRT2 | |
| SCHEMBL1994915 | 0.90 | PRKACA (0.55) | PRKACAPRKACGPRKACBCAMK2DSIRT2 | |
| SCHEMBL1991227 | 0.89 | PRKACA (0.45) | PRKACAPRKACGPRKACBCAMK2DSIRT2 | |
| SCHEMBL2001825 | 0.85 | CAMK2D (0.44) | PRKACAPRKACGPRKACBCAMK2DSIRT2 | |
| SCHEMBL1992218 | 0.84 | CAMK2D (0.49) | PRKACAPRKACGPRKACBCAMK2DGSK3B | |
| SCHEMBL1996421 | 0.84 | CAMK2D (0.50) | PRKACAPRKACGPRKACBCAMK2DGSK3B | |
| SCHEMBL1990666 | 0.83 | CAMK2D (0.43) | PRKACAPRKACGPRKACBCAMK2DSIRT2 | |
| SCHEMBL1993511 | 0.83 | CAMK2D (0.45) | PRKACAPRKACGPRKACBCAMK2DGSK3B | |
| SCHEMBL1997672 | 0.82 | PRKACA (0.43) | PRKACAPRKACGPRKACBCAMK2DSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079105-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-30 | — | — | WO | disclosed |
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | PRKACA 947/4885PRKACG 1317/4885PRKACB 1285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.