SCHEMBL19951572

SCHEMBL19951572

C=CC(=O)NC(C)(C)C(=O)NC(CO)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 3/20 0.44
ALDH1A1 P00352 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
MME P08473 6/20 0.36
TSHR P16473 1/20 0.35
TGM2 P21980 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ACE P12821 1/20 0.31
ACE2 Q9BYF1 1/20 0.31
CA2 P00918 2/20 0.31
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19963651 0.85 CYP2C9 (0.33) TGFBR1ALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL30374615 0.85 ALDH1A1 (0.33) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL19951581 0.79 NPSR1 (0.56) ALDH1A1CYP3A4CYP2C9CYP2C19MME
SCHEMBL23925357 0.78 ALDH1A1 (0.32) ALDH1A1CYP3A4CYP2C9CYP2C19TGM2
SCHEMBL6513640 0.77 TGFBR1 (0.52) TGFBR1ALDH1A1CYP2C19MMETSHR
SCHEMBL6513633 0.77 TGFBR1 (0.52) TGFBR1ALDH1A1CYP2C19MMETSHR
SCHEMBL19951565 0.77 FOLH1 (0.50) ALDH1A1CYP3A4CYP2C9CYP2C19MME
SCHEMBL19963562 0.76 ALDH1A1 (0.31) ALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL24334152 0.76 TSHR (0.37) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL7280005 0.75 TGFBR1 (0.44) TGFBR1MMEMEN1KMT2AACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023248020-A1 BLOCK COPOLYMERS GRAFTED TO POROUS POLYMERIC SUBSTRATE 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-12-28 WO disclosed
EP-3510041-B1 PROCESSES FOR SEPARATING AGGREGATED PROTEINS FROM MONOMERIC PROTEINS IN A BIOLOGICAL SOLUTION 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-05-31 EP disclosed
US-20200368694-A1 POLYMERIC SUBSTRATES WITH ATTACHED POLYMERIC CHAINS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2020-11-26 US disclosed
EP-3510041-A1 PROCESSES FOR SEPARATING AGGREGATED PROTEINS FROM MONOMERIC PROTEINS IN A BIOLOGICAL SOLUTION 3M Innovative Properties Company (US) 2019-07-17 EP disclosed
US-20190194250-A1 PROCESSES FOR SEPARATING AGGREGATED PROTEINS FROM MONOMERIC PROTEINS IN A BIOLOGICAL SOLUTION SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2019-06-27 US disclosed
US-20190194250-A1 PROCESSES FOR SEPARATING AGGREGATED PROTEINS FROM MONOMERIC PROTEINS IN A BIOLOGICAL SOLUTION SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2019-06-27 US disclosed
WO-2018048698-A1 PROCESSES FOR SEPARATING AGGREGATED PROTEINS FROM MONOMERIC PROTEINS IN A BIOLOGICAL SOLUTION 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-03-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190194250-A1 PROCESSES FOR SEPARATING AGGREGATED PROTEINS FROM MONOMERIC PROTEINS IN A BIOLOGICAL SOLUTION PRNP, APBA1, ECPAS TGFBR1 1331/4885ALDH1A1 4214/4885CYP3A4 4872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.