Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.30 |
| ▸ | LONP1 | P36776 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24711411 | 0.81 | TSHR (0.52) | TSHRNAALAD2FOLH1ALDH1A1CYP2C19 | |
| SCHEMBL20441093 | 0.79 | TSHR (0.38) | TSHRNAALAD2FOLH1ALDH1A1CYP3A4 | |
| SCHEMBL21117077 | 0.77 | GABRR1 (0.37) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19951572 | 0.76 | TGFBR1 (0.44) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19951581 | 0.69 | NPSR1 (0.56) | NAALAD2ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9248885 | 0.69 | ZDHHC20 (0.44) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19963651 | 0.68 | CYP2C9 (0.33) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30374615 | 0.68 | ALDH1A1 (0.33) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20098783 | 0.68 | ALDH1A1 (0.39) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19951579 | 0.68 | ALDH1A1 (0.39) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220120649-A1 | LIGAND-FUNCTIONALIZED SUBSTRATES WITH ENHANCED BINDING CAPACITY | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220120649-A1 | LIGAND-FUNCTIONALIZED SUBSTRATES WITH ENHANCED BINDING CAPACITY | ILK, EPCAM, ECPAS | TSHR 3878/4885NAALAD2 1119/4885FOLH1 520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.