Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | HTR2B | P41595 | 3/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.47 |
| ▸ | DNMT3A | Q9Y6K1 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29516922 | 1.00 | PTPN1 (0.51) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL19951672 | 1.00 | PTPN1 (0.51) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL18614717 | 0.90 | MEN1 (0.60) | HDAC6KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL18614718 | 0.90 | MEN1 (0.60) | HDAC6KDM4EALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8722574 | 0.81 | ELANE (0.54) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL15912060 | 0.80 | HTR1A (0.58) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL5446408 | 0.80 | NR4A2 (0.68) | ADRA1DKDM4EMEN1KMT2A | |
| SCHEMBL899036 | 0.78 | PTPN1 (0.48) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL30307409 | 0.78 | GALR3 (0.59) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL13100945 | 0.77 | PTPN1 (0.60) | PTPN1PTPN11HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4170347-A1 | GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS | 3B Pharmaceuticals GmbH (DE) | 2023-04-26 | — | — | EP | disclosed |
| US-20190359653-A1 | SELECTIVE PEPTIDE INHIBITORS OF FRIZZLED | GENENTECH INC (US) | 2019-11-28 | — | — | US | disclosed |
| US-10385028-B2 | Compounds for the treatment of neuromuscular disorders | NMD PHARMA A/S (DK) | 2019-08-20 | — | — | US | disclosed |
| EP-3509616-A1 | SELECTIVE PEPTIDE INHIBITORS OF FRIZZLED | H. Hoffnabb-La Roche Ag (CH) | 2019-07-17 | — | — | EP | disclosed |
| WO-2018049275-A1 | SELECTIVE PEPTIDE INHIBITORS OF FRIZZLED | GENENTECH, INC. (US) | 2018-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10385028-B2 | Compounds for the treatment of neuromuscular disorders | RYR1, CACNB1, RYR2 | PTPN1 2584/4885PTPN11 3236/4885HTR1A 2063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.