Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.45 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19951671 | 0.78 | PTPN1 (0.51) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL19951672 | 0.78 | PTPN1 (0.51) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL29516922 | 0.78 | PTPN1 (0.51) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL15912060 | 0.77 | HTR1A (0.58) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL1902196 | 0.76 | PTPN1 (0.67) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL15577909 | 0.75 | ELANE (0.57) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL15577623 | 0.75 | ELANE (0.57) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL899207 | 0.74 | FERMT2 (0.54) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL7369035 | 0.74 | PTPN1 (0.65) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL13100945 | 0.74 | PTPN1 (0.60) | PTPN1PTPN11HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621903-B1 | N-HETEROARYL COMPOUNDS | INTERVET INT BV (NL) | 2017-03-01 | — | — | EP | disclosed |
| CN-105294549-A | N-HETEROARYL COMPOUNDS | INTERVET INT BV | 2016-02-03 | — | — | CN | disclosed |
| CN-103189356-B | N-heteroaryl compounds | INTERVET INTERNATIONAL B.V. (NL) | 2015-11-25 | — | — | CN | disclosed |
| US-8877934-B2 | N-heteroaryl compounds | INTERVET INC. (US) | 2014-11-04 | — | — | US | disclosed |
| EP-2621903-A1 | N-HETEROARYL COMPOUNDS | Intervet International B.V. (NL) | 2013-08-07 | — | — | EP | disclosed |
| US-20130196993-A1 | N-HETEROARYL COMPOUNDS | INTERVET INC. | 2013-08-01 | — | — | US | disclosed |
| CN-103189356-A | N-heteroaryl compounds | INTERVET INT BV | 2013-07-03 | — | — | CN | disclosed |
| WO-2012041873-A1 | N-HETEROARYL COMPOUNDS | INTERVET INTERNATIONAL B.V. (NL) | 2012-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130196993-A1 | N-HETEROARYL COMPOUNDS | HNMT, SQLE, PIGO | PTPN1 3847/4885PTPN11 3551/4885HTR1A 1385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.