Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25337443 | 0.94 | SIGMAR1 (0.52) | AOC3ALOX5ADRA1ASLC6A3HDAC3 | |
| SCHEMBL1206390 | 0.88 | AOC3 (0.55) | AOC3ALOX5ADRA1ASLC6A3HDAC3 | |
| SCHEMBL15918918 | 0.85 | MAPT (0.51) | ALOX5ADRA1ASLC6A3HDAC3HDAC4 | |
| SCHEMBL25337380 | 0.85 | ESR1 (0.45) | AOC3SLC6A3TDP1LMNAKMT2A | |
| SCHEMBL25340496 | 0.82 | TAAR1 (0.49) | SLC6A3SLC6A4 | |
| SCHEMBL10592695 | 0.79 | AOC3 (0.56) | AOC3ALOX5ADRA1ASLC6A3CHRM2 | |
| SCHEMBL25337304 | 0.78 | TAAR1 (0.53) | HDAC1HDAC8MEN1KMT2AMAPT | |
| SCHEMBL15312924 | 0.78 | ALOX5 (0.71) | AOC3ALOX5ADRA1ASLC6A3HDAC3 | |
| SCHEMBL1952933 | 0.78 | ALOX5 (0.56) | AOC3ALOX5ADRA1ASLC6A3HDAC3 | |
| SCHEMBL3383363 | 0.78 | MAOA (0.57) | AOC3ALOX5ADRA1ASLC6A3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3509581-A1 | FORMULATIONS OF (R | Jazz Pharmaceuticals International III Limited (BM) | 2019-07-17 | — | — | EP | disclosed |
| CN-108635350-A | The method for treating vascular leak syndrome | 爱尔皮奥治疗有限公司 | 2018-10-12 | — | — | CN | disclosed |
| WO-2018048862-A1 | FORMULATIONS OF ( R)-2-AMINO-3-PHENYLPROPYL CARBAMATE | JAZZ PHARMACEUTICALS INTERNATIONAL III LIMITED (BM) | 2018-03-15 | — | — | WO | disclosed |