Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 11/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31208184 | 0.88 | NR1H2 (0.43) | NAMPTGPR119POLB | |
| SCHEMBL1689626 | 0.84 | MAPK1 (0.51) | GPR119POLB | |
| SCHEMBL29644487 | 0.84 | MAPK1 (0.51) | GPR119POLB | |
| SCHEMBL29385934 | 0.81 | AVPR1A (0.39) | CYP2C9 | |
| SCHEMBL27801145 | 0.81 | AVPR1A (0.39) | CYP2C9 | |
| SCHEMBL15685386 | 0.81 | NAMPT (0.44) | NAMPTGPR119CYP2C9 | |
| SCHEMBL1195132 | 0.81 | AVPR1A (0.47) | POLB | |
| SCHEMBL5578656 | 0.81 | TNKS (0.44) | GPR119 | |
| SCHEMBL1195130 | 0.81 | AVPR1A (0.47) | POLB | |
| SCHEMBL5578756 | 0.81 | ALDH1A1 (0.46) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960401-B2 | Spiropiperidine derivatives for controlling pests | SYNGENTA CROP PROTECTION, INC. (US) | 2011-06-14 | — | — | US | disclosed |
| US-7960401-B2 | Spiropiperidine derivatives for controlling pests | SYNGENTA CROP PROTECTION, INC. (US) | 2011-06-14 | — | — | US | disclosed |
| EP-1694677-B1 | SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-12-02 | — | — | EP | disclosed |
| US-20070135408-A1 | Spiropiperidine derivatives for controlling pests | SYNGENTA CROP PROTECTION, INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135408-A1 | Spiropiperidine derivatives for controlling pests | SYNGENTA CROP PROTECTION, INC. | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135408-A1 | Spiropiperidine derivatives for controlling pests | CHRM1, CHRM2, RER1 | NAMPT 3413/4885GPR119 2612/4885CYP2C9 515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.