Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | EPM2A | O95278 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.39 |
| ▸ | ALAD | P13716 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29013558 | 0.84 | PFKFB3 (0.45) | LMNAPTPN2MEN1KMT2ARAB9A | |
| SCHEMBL11437802 | 0.81 | DYRK1A (0.44) | GPR35BCL2L1STSPLK4AURKA | |
| SCHEMBL9262314 | 0.80 | ALDH1A1 (0.46) | GPR35BCL2L1LMNAKDM4EALAD | |
| SCHEMBL29481855 | 0.77 | LMNA (0.66) | GPR35BCL2L1LMNAPTPN2MEN1 | |
| SCHEMBL9578460 | 0.77 | ALDH1A1 (0.59) | GPR35BCL2L1LMNAKDM4EGLA | |
| SCHEMBL700588 | 0.77 | LMNA (0.66) | GPR35BCL2L1LMNAPTPN2MEN1 | |
| SCHEMBL498133 | 0.74 | BCL2L1 (0.59) | GPR35BCL2L1LMNAKDM4EGLA | |
| SCHEMBL30151656 | 0.74 | BCL2L1 (0.59) | GPR35BCL2L1LMNAKDM4EGLA | |
| SCHEMBL19964535 | 0.73 | CYP2A6 (0.40) | LMNAEPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL29466898 | 0.70 | KDM4E (0.48) | KDM4EEPM2APTPN2PTPN1PTPN22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107567443-B | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2023-04-28 | — | — | CN | disclosed |
| WO-2018048930-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |
| WO-2018048930-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |