Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 6/20 | 0.44 |
| ▸ | CLK1 | P49759 | 5/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 5/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262314 | 0.81 | ALDH1A1 (0.46) | GPR35BCL2L1ALDH1A1HPGD | |
| SCHEMBL19953250 | 0.81 | GPR35 (0.42) | DYRK1AGPR35BCL2L1STSHPGD | |
| SCHEMBL9578460 | 0.79 | ALDH1A1 (0.59) | DYRK1AGPR35BCL2L1ALDH1A1CA2 | |
| SCHEMBL11432426 | 0.77 | JAK2 (0.53) | AKR1B1ALDH1A1CA2CA12CA1 | |
| SCHEMBL2194399 | 0.77 | DYRK1A (0.71) | DYRK1ACLK1DYRK1BGPR35BCL2L1 | |
| SCHEMBL15697571 | 0.73 | GPR35 (0.61) | DYRK1ACLK1DYRK1BGPR35BCL2L1 | |
| SCHEMBL20593399 | 0.71 | MAOA (0.49) | DYRK1ACLK1DYRK1BALDH1A1CA2 | |
| SCHEMBL28671862 | 0.71 | CA12 (0.44) | DYRK1ACLK1DYRK1BALDH1A1CA2 | |
| SCHEMBL7574981 | 0.71 | STS (0.56) | DYRK1ACLK1DYRK1BALDH1A1CA2 | |
| SCHEMBL8208672 | 0.70 | HTT (0.43) | DYRK1ACLK1DYRK1BALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228173-A | Thiopyrano-benzopyrans, compositions and method of use thereof | FISONS LIMITED (GB) | 1980-10-14 | — | — | US | disclosed |