Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GRM7 | Q14831 | 4/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19953533 | 1.00 | FABP5 (0.43) | FABP5HDAC4HDAC7HDAC5ADRA2A | |
| SCHEMBL19953584 | 1.00 | FABP5 (0.43) | FABP5HDAC4HDAC7HDAC5ADRA2A | |
| SCHEMBL19960927 | 0.89 | KCNQ2 (0.44) | FABP5HDAC4HDAC7HDAC5ADRA2A | |
| SCHEMBL19953484 | 0.86 | GRM7 (0.43) | FABP5GRM7LMNAMEN1KMT2A | |
| SCHEMBL19960700 | 0.86 | GRM7 (0.43) | FABP5GRM7LMNAMEN1KMT2A | |
| SCHEMBL19960560 | 0.84 | HRH3 (0.45) | FABP5GRM7HRH3MTNR1AMTNR1B | |
| SCHEMBL19953514 | 0.82 | OPRM1 (0.43) | FABP5HRH3MTNR1AMTNR1BMAPT | |
| SCHEMBL19960585 | 0.82 | HDAC4 (0.48) | HDAC4HDAC7HDAC5ADRA2AADRA2B | |
| SCHEMBL19960839 | 0.82 | HDAC4 (0.39) | HDAC4HDAC7HDAC5ADRA2AADRA2B | |
| SCHEMBL19953537 | 0.82 | GRM7 (0.39) | FABP5GRM7HRH3MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |