Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 2/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | PYGM | P11217 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | UBE2I | P63279 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19953484 | 0.91 | GRM7 (0.43) | GRM7PYGLPYGMFABP5MEN1 | |
| SCHEMBL19953533 | 0.86 | FABP5 (0.43) | GRM7FABP5MEN1KMT2AEPHX2 | |
| SCHEMBL19953584 | 0.86 | FABP5 (0.43) | GRM7FABP5MEN1KMT2AEPHX2 | |
| SCHEMBL19953489 | 0.86 | FABP5 (0.43) | GRM7FABP5MEN1KMT2AEPHX2 | |
| SCHEMBL19953499 | 0.79 | FABP5 (0.39) | GRM7FABP5MEN1KMT2ATRPV1 | |
| SCHEMBL19953537 | 0.79 | GRM7 (0.39) | GRM7PYGLPYGMFABP5MEN1 | |
| SCHEMBL19960927 | 0.76 | KCNQ2 (0.44) | GRM7FABP5TRPV1EPHX2 | |
| SCHEMBL19960560 | 0.74 | HRH3 (0.45) | GRM7FABP5MEN1KMT2A | |
| SCHEMBL19953582 | 0.73 | GRM7 (0.41) | GRM7PYGLPYGMMEN1KMT2A | |
| SCHEMBL19953525 | 0.73 | ALDH1A1 (0.44) | GRM7FABP5MEN1KMT2ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |