Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 3/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | PYGM | P11217 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19953584 | 0.82 | FABP5 (0.43) | GRM7MEN1MAPTKMT2AHRH3 | |
| SCHEMBL19953533 | 0.82 | FABP5 (0.43) | GRM7MEN1MAPTKMT2AHRH3 | |
| SCHEMBL19953489 | 0.82 | FABP5 (0.43) | GRM7MEN1MAPTKMT2AHRH3 | |
| SCHEMBL19953499 | 0.82 | FABP5 (0.39) | GRM7TRPV1MEN1MAPTKMT2A | |
| SCHEMBL19953484 | 0.81 | GRM7 (0.43) | GRM7TRPV1MEN1MAPTKMT2A | |
| SCHEMBL19960700 | 0.79 | GRM7 (0.43) | GRM7TRPV1MEN1KMT2APYGL | |
| SCHEMBL19960927 | 0.74 | KCNQ2 (0.44) | GRM7TRPV1HRH3MTNR1AMTNR1B | |
| SCHEMBL19960560 | 0.70 | HRH3 (0.45) | GRM7MEN1MAPTKMT2AHRH3 | |
| SCHEMBL19953508 | 0.69 | HRH3 (0.46) | GRM7MAPTHRH3MTNR1AMTNR1B | |
| SCHEMBL19953514 | 0.68 | OPRM1 (0.43) | MAPTHRH3MTNR1AMTNR1BFABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | claimed |
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |