Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19953521 | 0.83 | CASP1 (0.45) | MEN1KMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL2743830 | 0.77 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL29037096 | 0.75 | CHRM2 (0.44) | MEN1KMT2ARAB9AALDH1A1KDM4E | |
| SCHEMBL19960560 | 0.75 | HRH3 (0.45) | MEN1KMT2AALDH1A1MAPTHSD17B10 | |
| SCHEMBL19125421 | 0.74 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL28743914 | 0.73 | KDM1A (0.41) | MEN1KMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL8565122 | 0.73 | KDM1A (0.41) | MEN1KMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL19960639 | 0.73 | ALDH1A1 (0.43) | MEN1KMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL17386339 | 0.73 | ALDH1A1 (0.50) | MEN1KMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL30892052 | 0.72 | MAPT (0.43) | MEN1KMT2AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |