Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 6/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19960661 | 1.00 | GRM7 (0.53) | GRM7ACEFEN1TACR2CNR1 | |
| SCHEMBL19953501 | 0.91 | GRM7 (0.61) | GRM7ACEFFAR1 | |
| SCHEMBL19953496 | 0.91 | GRM7 (0.61) | GRM7ACEFFAR1 | |
| SCHEMBL19953497 | 0.83 | GRM7 (0.55) | GRM7 | |
| SCHEMBL19960416 | 0.80 | GRM7 (0.60) | GRM7ACEFFAR1HTR2AHTR2C | |
| SCHEMBL19960496 | 0.80 | GRM7 (0.60) | GRM7ACEFFAR1 | |
| SCHEMBL19960866 | 0.79 | GRM7 (0.51) | GRM7TACR2CNR1CNR2NAMPT | |
| SCHEMBL20113084 | 0.79 | GRM7 (0.66) | GRM7 | |
| SCHEMBL19960865 | 0.79 | GRM7 (0.51) | GRM7TACR2CNR1CNR2NAMPT | |
| SCHEMBL19960841 | 0.78 | GRM7 (0.49) | GRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |