Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.49 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3697074 | 0.83 | NAMPT (0.53) | NAMPTTAOK3MAPK1ABHD6USP30 | |
| SCHEMBL3703899 | 0.83 | NAMPT (0.52) | NAMPTTAOK3MAPK1ABHD6USP30 | |
| SCHEMBL30771260 | 0.83 | NAMPT (0.52) | NAMPTTAOK3MAPK1ABHD6USP30 | |
| SCHEMBL19960673 | 0.81 | FABP5 (0.43) | NAMPTABHD6FABP5HRH3 | |
| SCHEMBL19960688 | 0.79 | FABP5 (0.42) | NAMPTABHD6FABP5EPHX2HRH3 | |
| SCHEMBL19960684 | 0.78 | HRH3 (0.39) | NAMPTFABP5EPHX2HRH3 | |
| SCHEMBL23257707 | 0.78 | NAMPT (0.54) | NAMPTTAOK3MAPK1ABHD6DDB1 | |
| SCHEMBL11929935 | 0.78 | ABHD6 (0.65) | NAMPTTAOK3MAPK1ABHD6DDB1 | |
| SCHEMBL29457612 | 0.78 | NAMPT (0.54) | NAMPTTAOK3MAPK1ABHD6DDB1 | |
| SCHEMBL19960916 | 0.77 | PRMT5 (0.46) | NAMPTFABP5HRH3PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |