Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19960916 | 0.81 | PRMT5 (0.46) | HRH3FABP5MTNR1AMTNR1BMAPT | |
| SCHEMBL19960688 | 0.80 | FABP5 (0.42) | HRH3FABP5EPHX2MTNR1AMTNR1B | |
| SCHEMBL19953754 | 0.78 | NAMPT (0.49) | HRH3FABP5EPHX2NAMPT | |
| SCHEMBL19960673 | 0.77 | FABP5 (0.43) | HRH3FABP5MTNR1AMTNR1BMAPT | |
| SCHEMBL19960680 | 0.75 | DRD2 (0.44) | HRH3FABP5MTNR1AMTNR1BMAPT | |
| SCHEMBL19960853 | 0.75 | FABP5 (0.38) | HRH3FABP5EPHX2MTNR1AMTNR1B | |
| SCHEMBL19953662 | 0.75 | EPHX2 (0.43) | HRH3FABP5EPHX2MTNR1AMTNR1B | |
| SCHEMBL19960635 | 0.70 | FABP5 (0.46) | HRH3FABP5MTNR1AMTNR1BMAPT | |
| SCHEMBL19960521 | 0.69 | FABP5 (0.44) | HRH3FABP5EPHX2MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL19953663 | 0.69 | FABP5 (0.45) | HRH3FABP5MTNR1AMTNR1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |