Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19960688 | 0.89 | FABP5 (0.42) | FABP5NAMPTHRH3MAPTMEN1 | |
| SCHEMBL19960916 | 0.83 | PRMT5 (0.46) | FABP5NAMPTHRH3MAPTGRM7 | |
| SCHEMBL19953754 | 0.81 | NAMPT (0.49) | FABP5NAMPTHRH3ABHD6 | |
| SCHEMBL19960684 | 0.77 | HRH3 (0.39) | FABP5NAMPTHRH3MAPTMEN1 | |
| SCHEMBL19960680 | 0.74 | DRD2 (0.44) | FABP5HRH3MAPTGRM7MTNR1A | |
| SCHEMBL19953699 | 0.73 | ACE (0.46) | FABP5HRH3MTNR1AMTNR1B | |
| SCHEMBL19953662 | 0.71 | EPHX2 (0.43) | FABP5HRH3MAPTGRM7ADAM17 | |
| SCHEMBL19960853 | 0.71 | FABP5 (0.38) | FABP5HRH3MAPTGRM7MTNR1A | |
| SCHEMBL22787538 | 0.71 | MAPT (0.58) | HRH3MAPTMEN1KMT2AGRM7 | |
| SCHEMBL19953512 | 0.69 | UBE2M (0.43) | FABP5HRH3MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |