Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19953762 | 0.84 | ALDH1A1 (0.46) | HDAC4HDAC7HDAC5EGFRSRC | |
| SCHEMBL14075302 | 0.81 | NOTUM (0.42) | HDAC4HDAC7HDAC5SRD5A1NOTUM | |
| SCHEMBL19960927 | 0.78 | KCNQ2 (0.44) | HDAC4HDAC7HDAC5TRPV1 | |
| SCHEMBL7834022 | 0.77 | TSHR (0.49) | SRD5A1KMT2ABRD4 | |
| SCHEMBL16250257 | 0.76 | KDM4C (0.44) | HDAC4HDAC7HDAC5NOTUMTRPV1 | |
| SCHEMBL30899464 | 0.76 | KDM4C (0.44) | HDAC4HDAC7HDAC5NOTUMTRPV1 | |
| SCHEMBL19953668 | 0.74 | HDAC4 (0.43) | HDAC4HDAC7HDAC5EGFRSRC | |
| SCHEMBL29960634 | 0.73 | SRD5A1 (0.38) | HDAC4HDAC7HDAC5SRD5A1NOTUM | |
| SCHEMBL30099061 | 0.72 | NOTUM (0.47) | HDAC4HDAC7HDAC5EGFRSRC | |
| Hydrochloric Acid SCHEMBL29960427 | 0.72 | SRD5A1 (0.38) | HDAC4HDAC7HDAC5SRD5A1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |