SCHEMBL1995396

SCHEMBL1995396

CC(=O)Oc1cc(F)cc(F)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.69
CYP4A11 Q02928 2/20 0.69
LMNA P02545 3/20 0.46
MAPT P10636 3/20 0.46
CYP3A4 P08684 2/20 0.46
KDM4E B2RXH2 2/20 0.46
MEN1 O00255 1/20 0.46
TTR P02766 1/20 0.46
TP53 P04637 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
BACE1 P56817 1/20 0.44
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
POLB P06746 1/20 0.42
PKM P14618 1/20 0.42
CYP19A1 P11511 1/20 0.42
ACHE P22303 2/20 0.41
ELANE P08246 2/20 0.41
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24445873 0.87 CYP4F2 (0.61) CYP4F2CYP4A11LMNAMAPTCYP3A4
SCHEMBL16950367 0.87 CYP4F2 (0.61) CYP4F2CYP4A11LMNAMAPTCYP3A4
SCHEMBL903399 0.86 CYP4F2 (0.59) CYP4F2CYP4A11LMNAMAPTCYP3A4
SCHEMBL16950366 0.86 CYP4F2 (0.59) CYP4F2CYP4A11LMNAMAPTCYP3A4
SCHEMBL27799880 0.86 CYP4F2 (0.59) CYP4F2CYP4A11LMNAMAPTCYP3A4
SCHEMBL16958028 0.86 CYP4F2 (0.59) CYP4F2CYP4A11LMNAMAPTCYP3A4
SCHEMBL31403416 0.84 CYP4F2 (0.57) CYP4F2CYP4A11LMNAMAPTCYP3A4
SCHEMBL16958599 0.82 CYP4F2 (0.56) CYP4F2CYP4A11LMNAMAPTCYP3A4
SCHEMBL17356485 0.82 CYP4F2 (0.56) CYP4F2CYP4A11LMNAMAPTCYP3A4
SCHEMBL16958601 0.82 CYP4F2 (1.00) CYP4F2CYP4A11LMNAMAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10483466-B2 P-doping cross-linking of organic hole transporters SIEMENS AKTIENGESELLSCHAFT (DE) 2019-11-19 US claimed
EP-3114715-B1 P-DOPING CROSS-LINKING OF ORGANIC HOLE TRANSPORTERS SIEMENS AG (DE) 2019-10-30 EP claimed
CN-109809383-A A kind of synthetic method of anti-cabbage black rot bacterium selenium carbon material 扬州大学 2019-05-28 CN claimed
US-20180198069-A1 P-Doping Cross-Linking Of Organic Hole Transporters SIEMENS AKTIENGESELLSCHAFT (DE) 2018-07-12 US claimed
CN-102797043-B Medicinal molecular fragment library and construction process thereof Tianli (Tianjin) Technology Co., Ltd. (CN) 2015-11-25 CN claimed
CN-103058931-B Four 2-(3', 5'-dihalo-benzyl) benzimidazole type novel compounds and preparation method thereof GUANGDONG TONESET SCIENCE & TECHNOLOGY CO LTD 2015-07-01 CN claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
CN-102797043-A Medicinal molecular fragment library and construction method thereof CBB NETWORK CO LTD 2012-11-28 CN claimed
CN-115054600-B Aromatic sulfonamide derivatives 拜耳制药股份公司 2024-06-14 CN disclosed
CN-116033897-A Phenol derivatives 住友制药株式会社 2023-04-28 CN disclosed
CN-115054600-A Aromatic sulfonamide derivatives 拜耳制药股份公司 2022-09-16 CN disclosed
CN-114984003-A Aromatic sulfonamide derivatives 拜耳制药股份公司 2022-09-02 CN disclosed
CN-109415321-B Aromatic sulfonamide derivatives 拜耳制药股份公司 2022-06-17 CN disclosed
US-10483466-B2 P-doping cross-linking of organic hole transporters SIEMENS AKTIENGESELLSCHAFT (DE) 2019-11-19 US disclosed
CN-1242007-A Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising such compounds, and methods of inhibiting beta amyloid peptide release and/or its synthesis using such compounds ELAND PHARMACEUTICAL CORP (US) 2000-01-19 CN disclosed
CN-1238779-A Methods and compounds for inhibiting beta-amyloid peptide release and/or its synthesis ELAN PHARM INC (US) 1999-12-15 CN disclosed
WO-1999059587-A1 ANTI-VIRAL COMPOUNDS ELI LILLY AND COMPANY (US) 1999-11-25 WO disclosed
EP-0863891-A1 (METHYLSULFONYL)PHENYL-2-(5H)-FURANONES AS COX-2 INHIBITORS MERCK FROSST CANADA INC. (CA) 1998-09-16 EP disclosed
CN-1151735-A Benzocycloalkylazolethione derivatives SYNTEX INC (US) 1997-06-11 CN disclosed
WO-1997014691-A1 (METHYLSULFONYL)PHENYL-2-(5H)-FURANONES AS COX-2 INHIBITORS MERCK FROSST CANADA INC. (CA) 1997-04-24 WO disclosed