Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.61 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1995396 | 0.87 | CYP4F2 (0.69) | CYP4F2CYP4A11CYP3A4LMNAMAPT | |
| SCHEMBL14351002 | 0.85 | CYP3A4 (0.63) | CYP4F2CYP4A11CYP3A4LMNAMAPT | |
| SCHEMBL320560 | 0.85 | CYP3A4 (0.63) | CYP4F2CYP4A11CYP3A4CA12CA1 | |
| SCHEMBL32667659 | 0.82 | CYP4F2 (0.42) | CYP4F2CYP4A11CYP3A4CA12CA1 | |
| Methoxymethane SCHEMBL29094017 | 0.81 | CYP3A4 (0.59) | CYP4F2CYP4A11CYP3A4CA12CA1 | |
| SCHEMBL16950367 | 0.80 | CYP4F2 (0.61) | CYP4F2CYP4A11CYP3A4LMNAMAPT | |
| SCHEMBL16950366 | 0.78 | CYP4F2 (0.59) | CYP4F2CYP4A11CYP3A4CA12CA9 | |
| SCHEMBL16958028 | 0.78 | CYP4F2 (0.59) | CYP4F2CYP4A11CYP3A4LMNAMAPT | |
| SCHEMBL903399 | 0.78 | CYP4F2 (0.59) | CYP4F2CYP4A11CYP3A4LMNAMAPT | |
| SCHEMBL27799880 | 0.78 | CYP4F2 (0.59) | CYP4F2CYP4A11CYP3A4LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4001336-A1 | POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE | Shin-Etsu Chemical Co., Ltd. (JP) | 2022-05-25 | — | — | EP | disclosed |
| CN-101326161-B | Novel compounds | ASTRAZENECA AB | 2013-04-17 | — | — | CN | disclosed |
| CN-101374804-A | Substituted diphenylethers, -amines, -sulfides and -methanes for the treatment of respiratory disease | ASTRAZENECA AB (SE) | 2009-02-25 | — | — | CN | disclosed |
| CN-101326161-A | Novel compounds | ASTRAZENECA AB (SE) | 2008-12-17 | — | — | CN | disclosed |