SCHEMBL16950366

SCHEMBL16950366

[CH2]c1cc(F)cc(OC(C)=O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.59
CYP4A11 Q02928 2/20 0.59
LMNA P02545 3/20 0.40
MAPT P10636 3/20 0.40
KDM4E B2RXH2 3/20 0.40
CYP3A4 P08684 2/20 0.40
MEN1 O00255 1/20 0.40
TTR P02766 1/20 0.40
TP53 P04637 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
BACE1 P56817 2/20 0.39
CYP19A1 P11511 1/20 0.37
POLB P06746 2/20 0.36
PKM P14618 1/20 0.36
ACHE P22303 2/20 0.36
ELANE P08246 2/20 0.35
HSD17B10 Q99714 1/20 0.34
GAA P10253 2/20 0.33
CA12 O43570 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1995396 0.86 CYP4F2 (0.69) CYP4F2CYP4A11LMNAMAPTKDM4E
SCHEMBL16960587 0.78 KMT2A (0.44) CYP4F2CYP4A11LMNAMAPTKDM4E
SCHEMBL16952194 0.78 LMNA (0.53) CYP4F2CYP4A11LMNAMAPTKDM4E
SCHEMBL24445873 0.78 CYP4F2 (0.61) CYP4F2CYP4A11LMNAMAPTKDM4E
SCHEMBL16950367 0.78 CYP4F2 (0.61) CYP4F2CYP4A11LMNAMAPTKDM4E
SCHEMBL16960965 0.77 LMNA (0.40) CYP4F2CYP4A11LMNAMAPTKDM4E
SCHEMBL16959280 0.77 LMNA (0.40) CYP4F2CYP4A11LMNAMAPTKDM4E
SCHEMBL16962213 0.77 LMNA (0.40) CYP4F2CYP4A11LMNAMAPTKDM4E
SCHEMBL16958028 0.77 CYP4F2 (0.59) CYP4F2CYP4A11LMNAMAPTKDM4E
SCHEMBL903399 0.77 CYP4F2 (0.59) CYP4F2CYP4A11LMNAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed