Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25745827 | 0.88 | DRD2 (0.41) | DRD2DRD4DRD3ALDH1A1HTR2A | |
| SCHEMBL24815007 | 0.86 | DRD2 (0.41) | TRPV4DRD2DRD4DRD3HTR2A | |
| SCHEMBL19954603 | 0.83 | TRPV4 (0.43) | TRPV4DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL25745811 | 0.80 | DRD2 (0.38) | DRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL24816270 | 0.80 | DRD2 (0.38) | TRPV4DRD2DRD4DRD3HTR2A | |
| SCHEMBL24815012 | 0.80 | DRD2 (0.40) | DRD2DRD4DRD3TLR9TLR8 | |
| SCHEMBL25745825 | 0.79 | DRD2 (0.39) | DRD2DRD4DRD3TLR9TLR8 | |
| SCHEMBL18161165 | 0.78 | DRD2 (0.43) | DRD2DRD4DRD3ALDH1A1POLB | |
| SCHEMBL19953968 | 0.78 | KDM4E (0.39) | DRD2DRD4DRD3ALDH1A1HPGD | |
| SCHEMBL25745817 | 0.78 | KDM4E (0.42) | DRD2DRD4DRD3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914706-B2 | N-substituted pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-13 | — | — | US | disclosed |