Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8469239 | 1.00 | POLB (0.33) | POLBSMN1; SMN2AKT1LMNAHTR1A | |
| SCHEMBL11564699 | 0.84 | DRD2 (0.39) | AKT1LMNA | |
| SCHEMBL435089 | 0.77 | LMNA (0.49) | POLBSMN1; SMN2LMNA | |
| SCHEMBL18475190 | 0.76 | CYP2D6 (0.41) | SMN1; SMN2LMNAHTR1AHTR2CALOX12 | |
| SCHEMBL12301094 | 0.76 | L3MBTL1 (0.35) | POLBSMN1; SMN2LMNAHTR2CL3MBTL1 | |
| SCHEMBL26304581 | 0.74 | LMNA (0.34) | POLBSMN1; SMN2LMNAHTR2CTP53 | |
| SCHEMBL17193796 | 0.74 | LMNA (0.34) | POLBSMN1; SMN2LMNAHTR2CTP53 | |
| SCHEMBL8473812 | 0.72 | HTR2C (0.34) | POLBSMN1; SMN2LMNAHTR2CTP53 | |
| SCHEMBL18469578 | 0.71 | LMNA (0.33) | POLBSMN1; SMN2LMNAHTR2CTP53 | |
| SCHEMBL8376689 | 0.71 | AKT1 (0.41) | AKT1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914724-B2 | C-aryl glycosid derivatives, pharmaceutical composition, preparation process and uses thereof | Shanghai De Novo Pharmatech Co., Ltd. (CN) | 2018-03-13 | — | — | US | disclosed |