Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21024103 | 0.82 | TRPV1 (0.42) | TRPV1TGFBR1LRRK2GAANR3C2 | |
| SCHEMBL21023833 | 0.82 | TRPV1 (0.40) | TRPV1TGFBR1GRIA2LRRK2GAA | |
| SCHEMBL18164067 | 0.80 | GAA (0.37) | TGFBR1LMNAGAANR3C2POLB | |
| SCHEMBL19954622 | 0.78 | GAA (0.37) | TRPV1TGFBR1LRRK2GAANR3C2 | |
| SCHEMBL19954552 | 0.78 | MAP3K12 (0.33) | TGFBR1IDO1NR3C2 | |
| SCHEMBL19954640 | 0.73 | CCNT1 (0.36) | TRPV1TGFBR1LMNANR3C2POLB | |
| SCHEMBL21023570 | 0.73 | NR3C2 (0.38) | TRPV1GAANR3C2POLB | |
| SCHEMBL19954602 | 0.72 | AR (0.41) | TRPV1GRIA2LRRK2 | |
| SCHEMBL19954668 | 0.72 | PLAT (0.36) | TRPV1TGFBR1GRIA2LRRK2NR3C2 | |
| SCHEMBL21023747 | 0.71 | DPP4 (0.35) | TGFBR1LMNAGAANR3C2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914706-B2 | N-substituted pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-13 | — | — | US | disclosed |