Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21024103 | 0.87 | TRPV1 (0.42) | GAANR3C2ALDH1A1LRRK2TRPV1 | |
| SCHEMBL21023833 | 0.87 | TRPV1 (0.40) | GAANR3C2LRRK2TRPV1TGFBR1 | |
| SCHEMBL16805955 | 0.81 | ALOX15 (0.45) | GAASMN1; SMN2ALOX15NR3C2ALDH1A1 | |
| SCHEMBL21023570 | 0.80 | NR3C2 (0.38) | GAASMN1; SMN2NR3C2ALDH1A1TRPV1 | |
| SCHEMBL22759269 | 0.79 | NR3C2 (0.40) | GAASMN1; SMN2ALOX15NR3C2ALDH1A1 | |
| SCHEMBL19954551 | 0.78 | TRPV1 (0.35) | GAANR3C2LRRK2TRPV1TGFBR1 | |
| SCHEMBL19954525 | 0.77 | SMN1; SMN2 (0.37) | GAASMN1; SMN2ALOX15NR3C2ALDH1A1 | |
| SCHEMBL19954609 | 0.76 | TRPV1 (0.42) | NR3C2LRRK2TRPV1HTR2AKCNH2 | |
| SCHEMBL19954668 | 0.74 | PLAT (0.36) | NR3C2LRRK2TRPV1TGFBR1IRAK4 | |
| SCHEMBL18164015 | 0.72 | GAA (0.38) | GAASMN1; SMN2ALOX15NR3C2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914706-B2 | N-substituted pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-13 | — | — | US | disclosed |