SCHEMBL19954687

SCHEMBL19954687

CCC(N)(CCCC1CCC1)C(C)(C)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.34
CHRM3 P20309 3/20 0.33
KDM1A O60341 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CHRM2 P08172 1/20 0.32
CYP2D6 P10635 1/20 0.32
CHRM1 P11229 1/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19954683 0.77 CHRM3 (0.37) CHRM3CHRM2CYP2D6CHRM1KCNH2
SCHEMBL19954765 0.76 TAAR1 (0.41) LMNA
SCHEMBL19954719 0.76 TAAR1 (0.46) LMNACYP1A2CYP2D6
SCHEMBL2791589 0.68 CHRM3 (0.51) SIGMAR1CHRM3LMNACYP1A2CHRM2
SCHEMBL3999140 0.67 KEAP1 (0.43) SIGMAR1CHRM3KDM1AMAOAMAOB
SCHEMBL19954685 0.66 TAAR1 (0.48) LMNACYP1A2CYP2D6
SCHEMBL24481796 0.66 CHRM3 (0.55) SIGMAR1CHRM3KDM1AMAOAMAOB
Hydrochloric Acid SCHEMBL11780644 0.66 CHRM3 (0.35) CHRM3
SCHEMBL12856740 0.65 SIGMAR1 (0.35) SIGMAR1KDM1AMAOAMAOB
SCHEMBL19954798 0.64 KIF11 (0.39) SIGMAR1CYP1A2CYP2D6KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9917273-B2 Cross-linking polymer and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-03-13 US disclosed