SCHEMBL19954797

SCHEMBL19954797

CCC(C)(c1ccccc1)c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
ALOX12 P18054 6/20 0.50
HSD17B10 Q99714 4/20 0.50
L3MBTL1 Q9Y468 4/20 0.50
ALOX15 P16050 3/20 0.50
TSHR P16473 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
MAPK1 P28482 2/20 0.50
PTGS1 P23219 1/20 0.50
SLC6A2 P23975 1/20 0.50
PTGS2 P35354 1/20 0.50
HTR2B P41595 1/20 0.50
HPGD P15428 4/20 0.47
MAPT P10636 9/20 0.45
GAA P10253 4/20 0.45
NR3C2 P08235 2/20 0.45
RAB9A P51151 1/20 0.45
CYP3A4 P08684 4/20 0.42
LMNA P02545 1/20 0.42
THRB P10828 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1242743 0.98 ALDH1A1 (0.46) ALDH1A1ALOX12HSD17B10L3MBTL1ALOX15
SCHEMBL284909 0.83 TAAR1 (0.48) ALDH1A1ALOX15TSHRMAPK1MAPT
SCHEMBL9473731 0.82 ALDH1A1 (0.52) ALDH1A1ALOX12HSD17B10L3MBTL1ALOX15
Ammonia Solution, Strong SCHEMBL28198861 0.81 TAAR1 (0.46) ALDH1A1ALOX15TSHRMAPK1MAPT
SCHEMBL19954756 0.80 ALDH1A1 (0.45) ALDH1A1ALOX12HSD17B10L3MBTL1ALOX15
SCHEMBL9330404 0.80 ESR1 (0.48) ALDH1A1ALOX12HSD17B10L3MBTL1ALOX15
SCHEMBL1576428 0.79 ALDH1A1 (0.59) ALDH1A1ALOX12HSD17B10L3MBTL1ALOX15
SCHEMBL12278122 0.78 NR3C2 (0.54) ALDH1A1ALOX12HSD17B10L3MBTL1ALOX15
SCHEMBL20674280 0.78 TAAR1 (0.50) ALDH1A1MAPK1MAPTNR3C2RAB9A
SCHEMBL8626323 0.77 ALDH1A1 (0.62) ALDH1A1ALOX12HSD17B10L3MBTL1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9917273-B2 Cross-linking polymer and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-03-13 US disclosed