Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052319 | 0.79 | LMNA (0.52) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL19954721 | 0.78 | — | — | |
| SCHEMBL29579600 | 0.76 | LMNA (0.41) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL7050458 | 0.76 | LMNA (0.41) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL30523885 | 0.75 | MEN1 (0.50) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL30523884 | 0.75 | MEN1 (0.50) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL20321512 | 0.75 | PDK2 (0.45) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL17961919 | 0.75 | PDK2 (0.44) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL7048388 | 0.74 | LMNA (0.46) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL29579333 | 0.74 | LMNA (0.46) | ESR1ESR2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9917273-B2 | Cross-linking polymer and organic electroluminescent element using same | IDEMITSU KOSAN CO., LTD. (JP) | 2018-03-13 | — | — | US | disclosed |