Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.61 |
| ▸ | CNR1 | P21554 | 10/20 | 0.61 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19040922 | 0.90 | CNR2 (0.53) | CNR2CNR1DRD2DRD3KIF11 | |
| SCHEMBL18559631 | 0.87 | CNR2 (0.54) | CNR2CNR1DRD2DRD3KIF11 | |
| SCHEMBL3435209 | 0.83 | CNR2 (0.46) | CNR2CNR1DRD2DRD3KIF11 | |
| SCHEMBL18879528 | 0.82 | CNR1 (0.49) | CNR2CNR1KIF11 | |
| SCHEMBL4698316 | 0.78 | CNR2 (0.45) | CNR2CNR1KIF11 | |
| SCHEMBL23026418 | 0.75 | KIF11 (0.44) | CNR2CNR1KIF11 | |
| SCHEMBL4698814 | 0.75 | KIF11 (0.42) | CNR2CNR1KIF11 | |
| SCHEMBL22432052 | 0.75 | KIF11 (0.46) | CNR2CNR1DRD2KIF11 | |
| SCHEMBL10279769 | 0.75 | CNR2 (0.46) | CNR2CNR1DRD2DRD3KIF11 | |
| SCHEMBL179266 | 0.75 | KIF11 (0.50) | KIF11CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9913843-B2 | Protein kinase C inhibitors and uses thereof | RIGEL PHARMACEUTICALS, INC. (US) | 2018-03-13 | — | — | US | disclosed |