Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18879528 | 0.90 | CNR1 (0.49) | KIF11CNR1CNR2CYP19A1ACSS2 | |
| SCHEMBL22022449 | 0.81 | KIF11 (0.48) | KIF11CNR1CNR2CYP19A1ACSS2 | |
| SCHEMBL3435209 | 0.81 | CNR2 (0.46) | KIF11CNR1CNR2ACSS2TSHR | |
| SCHEMBL4698316 | 0.79 | CNR2 (0.45) | KIF11CNR1CNR2ACSS2ALDH1A1 | |
| SCHEMBL22939513 | 0.78 | SHBG (0.55) | KIF11CYP19A1ALDH1A1CYP2A6LOXL2 | |
| SCHEMBL19040922 | 0.78 | CNR2 (0.53) | KIF11CNR1CNR2ACSS2TSHR | |
| SCHEMBL21891465 | 0.77 | KIF11 (0.44) | KIF11CNR1CNR2TSHRENPP2 | |
| SCHEMBL22432052 | 0.77 | KIF11 (0.46) | KIF11CNR1CNR2TSHRENPP2 | |
| SCHEMBL4698814 | 0.77 | KIF11 (0.42) | KIF11CNR1CNR2ENPP2GLA | |
| SCHEMBL179266 | 0.76 | KIF11 (0.50) | KIF11TSHRENPP2GLAPTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210054017-A1 | CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE | IONIS PHARMACEUTICALS INC (US) | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210054017-A1 | CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE | GNE, FUT6, GALNT13 | KIF11 1960/4885CNR1 3256/4885CNR2 3864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.