Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.54 |
| ▸ | CNR1 | P21554 | 4/20 | 0.54 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19954823 | 0.87 | CNR2 (0.61) | CNR2CNR1KIF11DRD2DRD3 | |
| SCHEMBL19040922 | 0.83 | CNR2 (0.53) | CNR2CNR1KIF11ENPP2GLA | |
| SCHEMBL18879528 | 0.82 | CNR1 (0.49) | CNR2CNR1KIF11ENPP2GLA | |
| SCHEMBL3435209 | 0.80 | CNR2 (0.46) | CNR2CNR1KIF11ENPP2GLA | |
| SCHEMBL4698316 | 0.78 | CNR2 (0.45) | CNR2CNR1KIF11ENPP2GLA | |
| SCHEMBL13781503 | 0.77 | GLA (0.44) | CNR2CNR1GLANR3C1NR3C2 | |
| SCHEMBL23026418 | 0.75 | KIF11 (0.44) | CNR2CNR1KIF11ENPP2GLA | |
| SCHEMBL4698814 | 0.75 | KIF11 (0.42) | CNR2CNR1KIF11ENPP2GLA | |
| SCHEMBL22432052 | 0.75 | KIF11 (0.46) | CNR2CNR1KIF11ENPP2GLA | |
| SCHEMBL179266 | 0.75 | KIF11 (0.50) | KIF11ENPP2GLAGRM2PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329280-B2 | Urea derivatives and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2019-06-25 | — | — | US | disclosed |
| US-9580421-B2 | Urea derivatives and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2017-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329280-B2 | Urea derivatives and uses thereof | UACA, RB1, FLT1 | CNR2 3573/4885CNR1 4170/4885KIF11 3183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.